Ciprofloxacin: Tularemia (Adults)

Treatment of tularemia with ciprofloxacin.

79/F Pneumonic Serology Gm 500 for 18 d Yes; yes 48/M Ulceroglandular Culture Gm 750 for 28 d Yes; no 65/F Typhoidal Serology 750 for 14 d No 65/F Ulceroglandular Serology 750 for 28 d No 40/F Ulceroglandular Serology Dox 750 for 28 d Yes; no 38/F Ulceroglandular Serology 750 for 10 d Yes 47/F Oculoglandular Serology Dox, Gm 750 for 28 d Yes; yes; yes 65/F Ulceroglandular Serology Dox 750 for 2...

Ciprofloxacin for treatment of tularemia.

Reply Sir—We would like to address Dr. Ise-man's concern [1] that our study [2] may be misleading. Dr. Iseman expresses his concern by emphasizing the absence of evidence that slow conversion of sputum smear results from positive to negative status is associated with an increased risk for transmission of Mycobacterium tuberculosis , treatment failure, and acquired drug resistance so long as app...

The potential of liposome–encapsulated ciprofloxacin as a tularemia therapy

Liposome-encapsulation has been suggested as method to improve the efficacy of ciprofloxacin against the intracellular pathogen, Francisella tularensis. Early work with a prototype formulation, evaluated for use against the F. tularensis live vaccine strain, showed that a single dose of liposomal ciprofloxacin given by the intranasal or inhalational route could provide protection in a mouse mod...

Tularemia.

Francisella tularensis is the etiological agent of tularemia, a serious and occasionally fatal disease of humans and animals. In humans, ulceroglandular tularemia is the most common form of the disease and is usually a consequence of a bite from an arthropod vector which has previously fed on an infected animal. The pneumonic form of the disease occurs rarely but is the likely form of the disea...

Etymologia: tularemia